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Natural Ways to Combat Inflammation and Stress (Hemp/PEA)

Coffee With Dr. Stewart. Season
Podcast Air Date: December 6, 2017

In this episode, Dr. Kendal Stewart discusses the differences between physical and emotional stress, and how they can affect your health over time. Other topics include using nutrition to overcome stressful situations, using your genetic profile to understand the reasons behind your stress, as well as considering nutritional elements for stress such as CBD and PEA for inflammation control.

Neurobiologix products mentioned in this episode:

Kara Stewart-Mullens: Welcome to Coffee with Dr. Stewart. I am your host Kara Stewart-Mullens. This show is to provide our listeners with up to date medical information from a leading neurotologist and nutrigenomic specialist. I invite you to sit back grab your favorite beverage or cup of coffee and let's have coffee with Dr. Stewart. Welcome everybody to coffee with Dr. Stewart. I am your host Kara Stewart Mullens and I am so glad to be back. I am here with Dr. Kendal Stewart. What's going on?


Dr. Stewart: Hi, Kara. How are you?


Kara: I'm good. Do you know how long it's been since we've done a show?


Dr. Stewart: Nope.


Kara: No. Time flies, right. It's been almost a year. And we're on show 34, and we had so many people e-mail us saying I love all your old shows, but where's the new ones.


Dr. Stewart: Sure. Let's do it.


Kara: Well first they all want to know what you've been up to. So what have you been up to in the past year?


Dr. Stewart: Actually, we’ve been up to a lot. We're taking our genetics panels and modifying them significantly, and we learned lots of new therapeutics that we need to talk about this season.


Kara: Okay, excited.


Dr. Stewart: We're starting to make some pretty significant advances and recovery of diseases we've never thought we could do anything about.


Kara: Really? Okay, well that's a lot of shows coming then. Today's show is about chronic stress. Everybody’s stressed out, right?


Dr. Stewart: Sure.


Kara: OK so there's three different types of stress right. There's stress that is routine stress, that's every day, we all have it from day to day. Stress brought on by sudden negative event, somebody passing, a divorce, there's terrible things that happen. And then traumatic stress is like a major accident, hurricanes, assaults, deaths. Those are all like three things that are really stress the person out.


Dr. Stewart: Absolutely.


Kara: So we've talked about it on previous shows, but we get a lot of questions about what wouldDr. Stewart recommend for stress. Okay, so we're going to get into that, but I do have one question for you. Have you changed any of your coffee choices?


Dr. Stewart: No.


Kara: No. You're still… What's your choice?


Dr. Stewart: Oh I just I love all kinds of coffee, but I’m kind of a coffee snob, I like the reserve.


Kara: Okay. Yeah, I knew you found something.


Dr. Stewart: I love Christmas Blend.


Kara: Christmas Blend, yeah that's good. That's good. Okay, I just had to get that out of the way because somebody asked me that the other day. I go, I don't know. All right, Dr. Stewart, what is your definition of chronic stress? What does that mean to you?


Dr. Stewart: Well. it's different for everybody. Everybody has a different definition. Now in my mind, even though you gave those three definitions, I really separate basically physical stress from emotional stress. And everybody likes to talk about it as one thing, but physical stress is really something that is – whether it's exercise, whether it's disease, or something of that nature – the nice thing about physical stress is there's a beginning and there's an end.


Kara: Okay. What do you mean by that?


Dr. Stewart: And what I mean is that's a finite length of time that it typically lasts. And whereas emotional stress is a completely different animal. The problem with emotional stress as you wake up first thing in the morning and you're thinking about it, you go to bed thinking about it. You wake up in the middle of the night thinking about it. and you can’t ever lay it down. So what I tell people is you'd rather go and run five miles a day and that be your stressor, because once you're done you're done. But when it comes to emotional stress you can't lay it down. So my patients – in particular patients who have children with autism, people with chronic diseases of those natures, loved ones who have chronic diseases – they have emotional stress that is just never ending. So what happens is, the way God designed our systems, is that we have to have mechanisms to handle each and every one of those. But what he really didn't design too well for a lot of us or we've genetically messed it up or the enemy is messed it up. However, you want to think about. Chronic stress cannot be dealt with on a never ending basis.


Kara: A never ending basis.


Dr. Stewart: No, you have to have some way to deal with it and you have to help yourself through it.


Kara: Okay. Well, it's a lot easier said than done. And so well that kind of links the chronic stress to health problems, that's kind of what we're going to talk about. So when you think of chronic stress, and do men get it more than women or women get it more than men?


Dr. Stewart: I actually think women get it more.


Kara: Well, that's what a lot of the literature so to speak says, that women carry their emotions. So with emotional stress might be a little bit higher for women?


Dr. Stewart: Sure. Well, the thing is stress is handled by everybody differently. And women love to internalize it. Most women are taught not to be complainers. The last thing you want to do is complain to your family. I always tell people who are having these types of things, come and tell Dr. Stewart about it. I don’t understand.


Kara: Right, don't whine.


Dr. Stewart: Don't profess it to your family or your friends because you look healthy on the outside. And especially Texas women are really good at that. No matter how bad they feel, they always get up and put on their makeup.


Kara: Yeah, we sure do, do our hair.


Dr. Stewart: Right. So Texas women are really bad about it, and I'd say southern women in general, and it's not to criticize any of the other…


Kara: Women, yeah.


Dr. Stewart: But in general we just need to understand that that women tend to suffer a lot more and they carry the burdens of their family a lot more.


Kara: I think everybody realizes that a lot of people are now understanding that there is some major issues going on, even though you look good from the outside. It used to be that if you're acting crazy and you look at on the outside, they just put you in the loony bin and they just put you on drugs, and that was the end of the day.


Dr. Stewart: Well instead of thinking about it as stress, I hate that term.


Kara: Okay, I didn't know that. What would you call it?


Dr. Stewart: Well here's the deal, so everything that that I have to define in my world, you come to me to figure out what to do about it. You don't come for me to tell you; oh you're stressed here's your…


Kara: Like some doctors


Dr. Stewart: Here's your pill. And a lot of times you completely get that wrong. Well here's the deal, we've got to understand what's really going on in the body. And what happens in stress is God's given us lots of mechanisms to actually handle these types of things. One of them is actually the more stress you get, whether it's physical or emotional, is you make endorphins. And so the body naturally makes endorphins, and these endorphins are opiates. And what they tend to do is, they tend to go to the nervous system, and they tell it to calm down, which is great. And so that's why a lot of people are hooked on exercise, a lot of people are hooked on opiates, unfortunately, and a lot of other things. But what really happens is the opposite happens with the immune system. So I always tell people you know chronic stress can kill you. Okay. And they say yeah. And I said, do you understand the mechanism of how that happens? Well, what happens is when you're stressed out you make endorphins that calms your nervous system. But guess what it tells the immune system?


Kara: To rev up.


Dr. Stewart: Tells it to rev up. And the reason it is, because it's a crisis, so the immune system needs to be on high alert, and that happens through the opiate receptor. And so the long and the short of it, is once when we deal with that chronic opiate stimulation of the immune system it turns up inflammation, as a general rule, across the body. And the stress, and the mental anguish, and the anxiety, and all the cognition and everything else, the inflammation gets worse in the nervous system.


Kara: Is that where the health problems start to happen?


Dr. Stewart: That’s where the health problems… You understand?


Kara: Yeah.


Dr. Stewart: So the natural state in the body of chronic stress is that you got immune hyperactive.


Kara: Inflammation.


Dr. Stewart: Inflammation. And what we now know is that inflammation in the brain is responsible for the good days and bad days fluctuation of most…


Kara: And you just said this brain?


Dr. Stewart: Mm hmm.


Kara: Okay.


Dr. Stewart: Most anxiety disorders, a lot of problems with all the things that people… The doctors love to say, oh it's just stress. Well you've got to be able to explain that, you got to do something about it, and that's not hand you a


Kara: I can tell you, I'm a stressed.


Dr. Stewart: Sure. So what we really want to do is, we want to recognize that. And we want to be able to go in there and blocked that opiate response, calm that immune system down. Because by calming the immune system down, we actually take a lot of the effects of the chronic stress off the body from a health perspective.


Kara: Okay. Well then let me get into something, because everybody's talking about hemp oils, CBD. Is that something that a lot of doctors are now recommending to calm that immune system down?


Dr. Stewart: Right. We’ll back up and let's talk about it. What's really happening is, when you deal with cannabis, hemp as a general rule, the CB1 receptors, these are found on the nervous system. That's actually for THC, Tetrahydrocannabinol.


Kara: That's the high component in it?


Dr. Stewart: That’s what makes people high. Now what's happening that's different on the microbial, which are the immune cells of the brain, that we have CB2 receptors, and that's where cannabidiol comes in.


Kara: CBD.


Dr. Stewart: Yeah. CB2 receptors are on the immune cells of the brain not on the brain itself. And so what they tend to do is calm the inflammation down.


Kara: So you're taking CBD or hemp oil that doesn't contain THC?


Dr. Stewart: Right.


Kara: And you can calm that receptor down, so that you can ease the anxiety.


Dr. Stewart: Right. And the other way to actually calm it is with Palmitoylethanolamide or PEA.


Kara: PEA, yeah a lot of people buy that from us, and I don't really quite understand what it does, and would you give it…?


Dr. Stewart: It does the same kind of thing in a different mechanism and it actually does through what we call a G coupling reaction. But basically it's a G protein coupling reaction that actually backdoors the CB2 system, and essentially just provides some natural calming now. PEA is more of an endo-cannabinoid which means it's one that our body makes. Most people understand that we make cannabinoids in our body.


Kara: Are we not getting enough, is that why PEA so popular to take is a dietary supplement?


Dr. Stewart: I just think we wear the system out.


Kara: We wear the system out.


Dr. Stewart: And then the last thing we use to really calm it, which is really been shockingly effective, is what I call ultra-low dose naltrexone.


Kara: That's a prescription.


Dr. Stewart: And a lot of people have read about low dose naltrexone. Now what I've found in a lot of my patients, because unfortunately I see complicated patients, I see lots of chemically sensitive patients. And so we have to be a little bit more cautious, so instead of just taking four and a half milligrams of naltrexone, which is what is written in the literature. We have to a lot of times ease into it, and we have patients on as little as a half milligram, and people line as much as six.


Kara: But that's a prescription you got to get from the doctor.


Dr. Stewart: That's a prescription, but it actually blends really nicely with your CBD and your PEA.


Kara: Well I've been taking the PEA now since it came out a few months ago, and I suffer from my neck pain. A lot of people I've talked to that the pain has produced. For me it has, it feels like it's calm down the pain that was shooting at my neck.


Dr. Stewart: Yeah. So the PEA has a dual role, because it's a G protein coupling effect it does have a pain effect and also an anti-inflammatory.


Kara: You're using big words there. So what's and easy term?


Dr. Stewart: I’m saying that for people who understand what I'm talking about.


Kara: Right. If I'm your patient and you're going to recommend PEA, what would you tell me?


Dr. Stewart: Well here's the deal. So a lot of people still are not quite comfortable giving hemp oil. The story actually goes that we didn't know what Trump was going to do with hemp oil. There was some talk that he didn't like hemp and was going to change things.


Kara: But it's everywhere.


Dr. Stewart: That hasn't happened, I think for the better. Remember all medications back in the 70s and 60s came from plants, so hemp is no different. But what happens is he… So what happened is we started putting out the word, we were like what are we going to do of hemp oil is not available. Well, in Switzerland they were using and have done a lot of studies on PEA, which is palmitoylethanolamide. And so we’ve been started using it, and you'll see a very becoming more common in the country, and actually blends really well with hemp and other things. And so the long and the short of it, when we deal with these types of things the toxicity of these agents is really just non-existent.You really can’t overdose in hemp oil, you really can't overdose in PEA. So you're really looking at very well tolerated substances. Now an interesting fact, I have a lot of patients who are ultra-chemically sensitive. They have allergies to everything.


Kara: Can't take medication.


Dr. Stewart: And they can't take hemp oil either.


Kara: Oh okay.


Dr. Stewart: A lot of them. But PEA has been one of those that even the most chemically sensitive patients, because it's an endocannabinoid, meaning our body makes it, they seem to tolerate it.


Kara: Oh, we had an email from a lady the other day that said on the bottom of her invoice, PEA has changed my life. And I was like that's got to be of your patients, but that's awesome to hear.


Dr. Stewart: Well and that's what it's about. We've got to help everybody.


Kara: I have lots of research on it, lots of case studies, and everything. Well let's get back to the stress part. We always talk about methylation on the show. So a lot of poor methylators. You can go back and listen, so we have several episodes on methylation. But methylation builds until a lot of this stress component, right.


Dr. Stewart: Well yeah, it's a back door effect.


Kara: A backdoor?


Dr. Stewart: Yeah. And what I mean by that if you… I'm always to back up and I'm going to talk to you about physiology, because as a general rule, doctors love to throw around words like stress and expect that you understand exactly what those…


Kara: No, you don't know what it is. You just know that you don't feel… You're just stressed.


Dr. Stewart: Well, what also happens is the brain always goes through a compensatory period. So if it's got a lot of stress, in essence when you're stressed and your body's under stress, you are at a lot more fragile situation from your environment. And I always tell people remember we're actually made to be in the woods.


Kara: Right, I love your wood story.


Dr. Stewart: Yeah, so if we were camping.


Kara: You’ve said this a few times.


Dr. Stewart: A bear came in the camp. The bear is probably going to get the weakest person. Now, the thing is what happens during stress from on neurotransmitter perspective is that we tend to take glutamate, which is a stimulant to the brain, and we tend to flood the brain with glutamate.


Kara: Is that a good thing?


Dr. Stewart: No, not in a general rule, not for long periods of time. And we'll talk about that, I know, in another show. But glutamate then asks the cells to start chewing up more energy, it puts them on high energy status. And so if methylation, you want to think about methylation from a standard brain function is the amount of gasoline that you have in your car. So unfortunately, if you're not methylating and you making 33% of your methylation.


Kara: Right, because you have a mutation.


Dr. Stewart: Correct. So you've got 33%, you're waking up with a third a tank of gas. Now you got a nervous system, that’s just like driving a car faster, you're going to burn more. And all of a sudden you become brain dead afternoon.


Kara: Right. You have no energy left.


Dr. Stewart: No energy and your brain doesn't work right.


Kara: Well that happens in a lot of stressful situations. You go through this emotionally stressful situation and then you're exhausted.


Dr. Stewart: Well and here's the thing. Think about it from a financial standpoint, you're going to have some savings in the bank because there's things that come along in your life that sometimes need money that you didn't expect. And you're going to run out of money if you're not careful, so we've always got to have extra. Now the problem is…


Kara: Same with methylation.


Dr. Stewart: Here's the problem, if you haven't been methylating, and we have a lot of inflammation. If we don't calm that inflammation down first before we start to methylate, we're actually going to make you feel worse. Because we’re going to feed the immune system that nutritional element, and it's already going off. So you got to make sure that the way you do this, the elegant and understanding, nutrition. And how it works is to actually get the timing right, it's just like cooking.


Kara: Okay. I want to get into the next topic. I think we're in a break right here, but I want to discuss this misconceived term over methylation and get this on record, and let the expert explain why that does not exist. So ladies and gentlemen we are right back with Coffee with Dr. Stewart.


[Commercial Break]


Kara: All right, everybody we're back with Coffee with Dr. Stewart. We are in the middle of talking about chronic stress, a little methylation. What we can do to help those who are suffering from chronic stress issues that affect the nervous system, immune system. Hey, Dr. Stewart we're back. A big break there, right. Big break. Okay, so Dr. Stewart we had cut to commercial and we were talking about methylation. And I want to clear up something, because I get emails all the time through neurobiologics, and three other doctors and everything what about over methylation? What is over methylation? My patients are over methylating. But you say, it's just not biochemically possible. So can you explain that to us so we can clear the air here on that?


Dr. Stewart: I get this question every time I lecture. I want to cover a few things. Now people throw out over methylation as kind of a generalized term, and they really love to link it to methyl folate, which really is just not proper.


Kara: But that's what you take to methylate?


Dr. Stewart: Well, but that's not necessarily true. Okay. We do have these chemicals called methyl donors carine, choline, methionine, trimethyl glycine.


Kara: Those are like what’s in a Full Focus?


Dr. Stewart: Those are like what's in Red Bull. Okay. Now if you drink too much Red Bull and have too much taurine, like if you drink a whole gallon of Red Bull.


Kara: Like I used to.


Dr. Stewart: You may actually over methylate, because you're using a methyl donor. But that is not what's happening with methyl folate.


Kara: Okay, the methylation support.


Dr. Stewart: And so with methyl folate, what's going on is, it's a very simple biochemical understanding, and all biased chemists know it. Every enzyme has what we call a rate limiting step, which means it can only work at a certain pace no matter what you do to it.


Kara: No matter how much you give it?


Dr. Stewart: So if you give it extra… What everybody doesn't understand, they'll say, well you'll put in too much and you'll create too much on the back side. Well, that is impossible to do, because the enzyme can only make as much as it's capable of making.


Kara: Is it like the sense for, it can only take what it needs and then disperses the rest?


Dr. Stewart: If you’ve got a small pipe, and you've got a huge lake behind it or a small lake behind it, that pipe will still only carry the amount of water or methyl folate no matter how much you have behind it, whether it's a huge lake or a small lake.


Kara: So that's not over methylation, because you can’t get more through.


Dr. Stewart: I got a huge lake that it's going to go through a lot more.


Kara: It doesn't work that way.


Dr. Stewart: Doesn't work that way. So the problem is a lot of people love to think these are the symptoms of under methylation.


Kara: What do you mean under methylation?


Dr. Stewart: Well, so brain fog, low dopamine, low serotonin, not happy, those are under methylation. So if I put methyl folate in and I get the opposite, I get anxiety and stress and all that that, but I must have over methylate.


Kara: And that's not it.


Dr. Stewart: Well what's really happened and what we've been able to actually clinically ascertain is that when you don't calm the inflammation down – inflammation plays a big role in all the symptoms over methylation.


Kara: Well he can't see the quotes. He's being sarcastic there with the term over methylation.


Dr. Stewart: Okay. And what that means is that you've actually put methyl folate into an immune cell that was still going off, and you just gave it extra gas and it created more inflammation.


Kara: So it just turned up the immune system and that's why you get anxiety in all this.


Dr. Stewart: So it's a way for people to describe symptoms, but it's not a way for us to describe it biochemically.


Kara: So in medical terms that's just not correct.


Dr. Stewart: It's not correct.


Kara: Now what would over methylation be defined as methyl donor overstimulation?


Dr. Stewart: That is, in theory, correct. I mean, you can take too much of methyl donors. Okay. But it's not what people are talking about with over methylation.


Kara: Well I think there's just a lot of confusion in the medical community.


Dr. Stewart: Well sure there is, and they love to think about it, but they've never thought about it like that. So I just tell people wanting to sit down and we'll talk about it. And you've got to understand, but biochemists are bad because they've created it, but they've forgotten some primary rules about chemistry. Which is the rate limiting step of enzyme known the rate limiting step, no matter…


Kara: The right limiting step.


Dr. Stewart: No matter how much O factor I give to that enzyme, the enzyme is not capable of running faster than its highest rate.


Kara: That’s like a sponge like it can only take so much water. You can't just put it in, and it'll take twice as much. So it's not going to cause that that over stimulant.


Dr. Stewart: Correct. Now if you have let's say I never drink coffee, and I go to Starbucks and I slam your regular cup, it's going to jack me up. But that doesn't mean that I overdid it.


Kara: Well, we have a lot of people that start methylation products with us, because that's what we're known for, a lot of our product line. And they come back, and they do a little bit of the cream – the Methylation Pro or the Methylation Complete – and they have that reaction. They're like oh my God, it revved me up. We always tell them to back down, that they're going too fast.


Dr. Stewart: That really meant they needed it.


Kara: Well it does mean that they need it, but it could also be an inflammatory issue that you need to look at.


Dr. Stewart: Didn't control the inflammation. So here's the deal with inflammation. The psychiatry world got turned upside down about late 2015 when all these new PET scans were showing inflammation present in the brain. And anxiety, ADD, sleep disorder, all these very common things, we had inflammation. And so now if you read the psychiatric literature they love to talk about neurotransmitters, but they also talk about this neuro inflammation. And so what's happened is, good days and bad days, neurotransmitters can't change quickly. In fact, a neurotransmitter, if you're going to deplete it, it's going to take several days if not a couple of weeks. You can't become depressed overnight. You understand?


Kara: It takes a few days.


Dr. Stewart: Correct. But inflammation can change within the hour. So you literally go from no inflammation to highly, or no anxiety highly.


Kara: If you eat something that causes inflammatory.


Dr. Stewart: So what that does is the inflammation is what causes that. Now over methylation reactions are rapid. They are not over weeks.


Kara: And this is this is over methylation, just because of…


Dr. Stewart: What they're calling over methylation.


Kara: What they're calling, but it's not. Yeah I guess, instead of using over methylation what term would you come up with?


Dr. Stewart: Well I would say, it's inflammatory aggression use.


Kara: Inflammatory aggression. I wish people would start saying that, because it's confusing a lot of patients and they don't all get to go see you. You got a two year wait list so.


Dr. Stewart: No, but I'll be glad to sit down and discuss this with any biochemist.


Kara: Right. We're just trying to get it out there for you know medical providers and patients to understand. Well give me a perfect… Like I said we have people are calling go, oh my gosh I can't take, my child went wild when I put the cream on him. So what…?


Dr. Stewart: Means you have a different problem.


Kara: Right. So what would you recommend to those people?


Dr. Stewart: Well they need to get their inflammation under control before they ever even start to methylate.


Kara: OK. So you're thinking the PEA, or some hemp oil. Any other nutrients?


Dr. Stewart: I mean we preach that at our clinic nonstop. We never methylated before two or three weeks.


Kara: Okay, you start with the immune system?


Dr. Stewart: Actually, we don’t have machines to measure inflammation in the nervous system or devices. And so we can always recognize who has inflammation and who doesn't. And we always say you put this methylation or this methyl folate in before you're ready you're not going to like me.


Kara: So what do you recommend? What do you always start with then?


Dr. Stewart: We always start with whatever is appropriate for inflammation.


Kara: The PEA and the hemp oil, what else is there?


Dr. Stewart:
Low dose naltrexone.


Kara: Okay, what if they can't get to a doctor?


Dr. Stewart: Well so having a good about microbiome.


Kara: Is that...so probiotic?


Dr. Stewart: Restore probiotics, beta glucans, so things that actually modulate and calm down the immune system. Pregnenolone, vitamin D….

Kara: Now tell me a little bit about pregnenolone, because that's a hormone support product.


Dr. Stewart: Now pregnenolone is the precursor to all steroid hormones. Cholesterol converts to pregnenolone. And so pregnenolone makes everything from cortisol to progesterone to testosterone to estrogen to aldosterone to other steroids. So the other thing with pregnenolone, pregnenolone by itself is not really truly active as a steroid. It has to be converted by something.


Kara: Right, it's a co-factor.


Dr. Stewart: Well it's not a co-factor, it's a precursor.


Kara: Precursor.


Dr. Stewart: Yeah, which means it has to be converted into something to be biochemically active. And so a lot of times by adding that, if you are under chronic stress and your adrenal is under a chronic drain. Putting some pregnenolone you actually making sure that you're delivering enough substrate to continue the cortisol production, and the progesterone, your testosterone.


Kara: Yeah, I need to get back on that.


Dr. Stewart: Right, makes sense.


Kara: Well tell me a little bit. So we went down the road of stress and we talked about some things, but what about stress and hormones. How did those go together?


Dr. Stewart: Well here's the deal. So hormones, no hormones have to be divided into a big category. So in stress you got to worry about your thyroid a lot. Because the problem is, especially if you're having to take thyroid. Remember if I'm under a stressful situation my brain will secrete TSH from the pituitary. It'll tell my thyroid to rise because I'm under stress, because I need to make more energy to handle the stress. But if you're on thyroid and you're taking the same dose every day and you have no way to raise it, chronic stress will chew up the thyroid. And where does your level go?


Kara: Low.


Dr. Stewart: It goes down. Now what everybody doesn't understand is that thyroid’s main function is to actually tell the cell to make energy. So as the thyroid starts dropping down the energy reduces. And what are the big energy utilizing organs of the body?


Kara: The brain a brain.


Dr. Stewart: The brain and the immune system.


Kara: Is your mitochondria to suffer as well?


Dr. Stewart: Well that's your mitochondria, that’s where the energy comes from. Well, the thyroid tells the mitochondria, the thyroid does other things, so I don't want people to get…


Kara: There's a lot of things.


Dr. Stewart: But what it really tells is those mitochondria to rev up and increase the metabolic rate of the cell.


Kara: So in women that have a lot of stress and they gain a lot of weight is that because that thyroid is not producing?


Dr. Stewart: That's a real complicated…


Kara: I love to get the complicated.


Dr. Stewart: When it comes to inflammation and progesterone from a steroids for women, and testosterone for men, are the primary long term steroids. People who do not handle stress as well, are people who have lost their progesterone or their testosterone. Stress can affect you quite a bit more after you've gone through menopause or andropause, or even if you're on birth control pills. Okay. And so that always has fail safes in place. So for inflammation control, in a standpoint of the body we have a long term steroid which is progesterone or testosterone. We have the short term steroid which is cortisol. We have vitamin D, which at most people to understand is a secosteroid. Vitamin D meaning higher, can help you some. And then we have glutathione under that, which is another inflammatory control agent as well as a chemical detox clearer.


Kara: Okay. So for a woman or a man under high stress these are things to chip away at to take a look at.


Dr. Stewart: And then you've got to check your thyroid and make sure it maintains it fairly well. And in fact, if you are on thyroid and you're having to supplement your thyroid, many times during chronic stress we have to bump it up.


Kara: Oh very interesting, very interesting. Well let me ask you about why the gut seems to always have some problems around that stressful times. Because everybody's always wondering about the digestive system and how stomach pains happened a lot when you're stressed out, and you start to have bowel issues. How does that get affected?


Dr. Stewart: Well what organ is easiest to tell when there's inflammation? The skin is probably the easiest.


Kara: Right, because it gets inflamed or itchy.


Dr. Stewart: What's the second?


Kara: The gut, because your stomach hurts.


Dr. Stewart: Right. And the problem with the gut is if the gut is inflamed it doesn't absorb things very well. Okay. So you get and do irritable bowel and you get into a lot of different scenarios. There's also the problem with having inflammation in the gut, as the guts as big as the tennis court if you stretch it out.


Kara: Right, you said that before.


Dr. Stewart: And so creating inflammation from that stress the gut is a very, very impressive source of inflammation. And so when the gut gets involved it becomes many degrees more severe undergoing that stressful situation.


Kara: What can help you out with that? Because I mean I know it, I get more heartburn when I'm stressed out.


Dr. Stewart: Well, heartburn is really about the nervous system. Once the inflammation spreads to the nervous system lots of things go wrong.


Kara: Oh, great.


Dr. Stewart: Exactly. And so, in general, what you want to do is, there's no doubt that you will handle stress better if you have some form of inflammation control.


Kara: Such as a probiotic or a beta glucan.


Dr. Stewart: I’m not just talking about the gut. I'm talking about using hemp oil…


Kara: Everything.


Dr. Stewart: Or PEA or other things that you will lessen the effects of the stress on the nervous system, on the gut, on the inflammatory immune processes of the body.


Kara: So let's say nobody has stress right now, they’re perfect and they're just all living life like yeah, this is awesome. But you always talk about this traumatic event second pop up. We talked about this all of a sudden you get a death, or a divorce, or something. Would this nutritionally prepare the person to be able to handle that, so they don't get so….?


Dr. Stewart: Yeah, it's always best to be proactive. The problem is before genetics came along we really had trouble being proactive. Well, in a way, you were just getting the doctor's best guess, even though we would use blood markers. But genetics now allow us to prepare the body and understand exactly what the individual person needs. And basically, it's just always better to be proactive.


Kara: Well you just let me into my last question for the show. What genetics would you look into if you've got someone under some high stress, they've got their genetic report.


Dr. Stewart: You look at everything.


Kara: No. Well I mean, what would a person, like inflammatory markers in particular. Are there certain ones that you always pay attention to more than the others?


Dr. Stewart: Well you're simplifying it too much.


Kara: Well, I know.


Dr. Stewart: So the answer is you've got to look at the entire thing, the stress affects the whole body. Okay. So you've got to look at methylation and all the markers there. You've got to look at the B12 methylation, as well as folate. You've got to look at the mitochondrial stress, you've got to look at the detox and how the body's prepared. You got to look at the inflammatory markers, external and internal. You've got to make sure that you understand exactly how the immune system is going to respond to this overall stress. I mean the whole idea is you've got to be able to understand the whole body's physiology, because it all works together.


Kara: This is why a lot of genetic tests are going through doctors now.


Dr. Stewart: Correct.


Kara: Right. Like the one you created it goes through a doctor, because it's really, really complicated There's a lot of things to look at. But with the inflammatory markers, I mean the gluten sensitivity could you look at that if you had your live well report or something of that nature, and then you just kind of chip away at what you need to stay away from externally.


Dr. Stewart: I sometimes think it's so simple, because I do it all day.


Kara: Right, and it's not.


Dr. Stewart: I always have visiting doctors that come and spend the day with me, and they always remind me how complicated it is. So you learn. And unfortunately, a lot of people feel a little bit lost, because they haven't found that doctor to help support them.


Kara: I think we're getting more doctors that are able to help.


Dr. Stewart: Yeah, but they learn and do things like that. But just it's always best, I mean precision medicine is what it is. We want to be able to precisely interpret what you need and what you don't need. And I always use a simple analogy. I mean we have very smart patients. So if you're going to make a vegetable soup you're smart enough to go look in your fridge, open it up and see what you have, and so you only go to the store and buy what you need. Because if you skip the fridge, you're going to have to go the store and buy everything.


Kara: Everything. Well with that nice words of wisdom there at the end. Everybody, we are going to wrap it up for the day. But we appreciate you joining us on this beautiful afternoon. I'm Kara Stewart Mullens, and thank you for joining Coffee with Dr. Stewart. If you have questions email info@neurobiologix.com, or you can call us at 866-500-5388. Thank you, Dr. Stewart I appreciate it.


Dr. Stewart: You're very welcome.


Kara: All right have a good one. Bye-bye. God bless.


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Speaker:
The views expressed by show hosts or their guests are their own and shall not be construed in any way as advice and place of your own medical practitioners. We encourage you to seek professional advice or care for any problem which you may have.