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Issues With Converting Folic Acid

It is estimated that nearly half of our world population has what is known as the MTHFR gene mutation. Researchers and physicians alike are beginning to recognize the gene’s complexity and how that complexity is capable of impacting every facet of our health—as well as how we can use methylated vitamins to improve our health.

What are MTHFR mutations?

An MTHFR mutation refers to an anomalous variant of the gene methylenetetrahydrofolate reductase (shortened to MTHFR), which is responsible for production of a crucial enzyme of the same name. This enzyme acts as a catalyst to a bodily process known as methylation, the addition of a methyl group to a source substance, such as a toxin or unrefined nutrient, in order to produce a new chemical. Methylation, then, is a process which is imperative to proper function all throughout our bodies. It is involved in the production of neurotransmitters, generation of energy, regulation of hormones, transformation of nutrients, and detoxification. When a mutation in the MTHFR gene manifests itself, it results in less efficient methylation, which is suspected to be a potential root for an extensive list of health issues, both physical and mental.

How Can We Stimulate Methylation?

Specifically, MTHFR activates the folic acid we intake through our diet, converting it into a form usable by our cells (5-MTHF). That activated substance, methylfolate, then goes on to stimulate the process of methylation. Those affected by the MTHFR mutation are unable to process folic acid in a healthy manner, and as such, they are encouraged to incorporate supplements of active folate into their dietary habits. Stimulating methylation can alleviate a great number of stubborn, otherwise unexplained symptoms, such as lack of energy, mood issues, sleep pattern instability, among many other near-immune issues. Adding methylfolate supplements to a nutritional regimen may help. Call 866-500-5388 or view our podcasts section for more educational information from our experts and to learn more about our genetic mutation supplements.

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methylation support vitamin b12 supplement  60 count Methylation support supplement 2 oz

Methylation Support - Step One

Supreme bioactive fast-dissolving tablets.

For those who may be sensitive to supplementation but are looking for methylation support, this is considered Methylation Support: STEP 1. Once this is tolerated well then you may consider moving to Methylation Support: STEP 2 with our Methylation Complete Fast Dissolves.

Methylation Support - Step One® combines the active coenzyme form of vitamin B12, methylcobalamin, with an active form of folate, Metafolin®* L-5-methyltetrahydrofolate. This bioactive formula was created to bypass normal absorptive mechanisms for vitamin B12 and folate which may be lacking due to aging, diet, or gastrointestinal issues.

Fast-dissolving tablets allow for quick release into the bloodstream. Vitamin B12 and folate play an integral role in DNA synthesis and thus are essential to cell division and proper functioning of virtually all tissues in the body.

Vitamin B12 and folate also participate in methylation and proper metabolism of homocysteine, a potentially toxic metabolite of methionine. Dietary B12 can be reliably obtained only from animal products and is a singularly difficult vitamin to absorb. Active B12-Folate may be especially beneficial for vegetarians and persons with impaired stomach absorption issues.


Ultimate Methylation Support In One Cream!

BioActive B6, B12, Methyl Folate (5-MTHF), Vitamin D and A Small Amount of Vitamin K For Delivery
*Enhanced Liposomal Delivery System*


Advanced Topical Cream for Neurological, Nervous & Immune System Support / Ultimate Methylation Support

The addition of Vitamin K in this methylation support cream is recommended for those who are hindered by a methylation deficiency and/or a VDR Taq genetic polymorphism which inhibits the person's ability to absorb vitamin D at the cellular level without the cofactor Vitamin K. Impaired vitamin D function due to this polymorphism can result in significant immune weakness, early bone loss and increased risk of cognitive decline and mood issues.*
As a solution, our unique topical delivery system, assures that our professional- grade Methylation Pro promotes and enhances the methylation processes needed to improve the production of glutathione, increase Vitamin D levels and allow maximum B12, B6 and vitamin delivery to the nervous and immune systems. This potent nutrient-rich cream may help maximize and aid in:

  • Mood Improvement & Stabilization*
  • Mental Focus & Concentration*
  • Organization Skills*
  • MTHFR Mutations*
  • Short Term Memory Loss*
  • Supporting a healthy sleep cycle*
  • Immune Function and well-being*
Such nutrients as Pyridoxal 5-Phosphate (B6) and Vitamin B12 in a methylated form called methylcobalamin (Methyl B12) and hydroxycobalamin (Hydroxy B12), natural Vitamin D and K1 assist the body neurologically and physically.

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What Does A VDR Taq Genetic Mutation Mean To You?

The Vitamin D Receptor is a member of the nuclear receptor family. Upon activation by vitamin D, the VDR causes the activation or deactivation of protein production by the cell.

Impaired vitamin D function can result in significant immune weakness, as well as early bone loss, an increased risk of cognitive decline and mood issues.*