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Part 2: Mitochondria - Why Are We So Tired?

Coffee with Dr. Stewart: Season 2 - Episode 10

Podcast Show Date: December 2, 2015

Kara Stewart-Mullens: Neurobiologix proudly presents season two of Coffee with Dr. Stewart. This show will provide our listeners with up to date medical information from a leading neurotologist and neuro-immune specialist. With Dr. Stewart’s broad medical knowledge, we will discuss how he helps his patients with issues such as ADD, migraines, hormones, sleep, fatigue, methylation, autism, genetic mutations, and nutritional protocols. I am your host Kara Stewart-Mullens and I invite you to sit back, grab your favorite beverage or cup of coffee and let’s have Coffee with Dr. Stewart.

Hello everybody and thank you for joining us on another episode of Coffee with Dr. Stewart. I am your host Kara Stewart-Mullens and, as always, we have Dr. Kendall Stewart. How are you?

Dr. Stewart: I’m doing great Kara.

Kara Stewart-Mullens: Good. You had a good week?

Dr. Stewart: Oh yeah. I’m jacked on coffee right now.

Kara Stewart-Mullens: Oh I can tell. Last week it was me and now this week it’s you. I’m a little tired today I have to admit. I had a lot going on last night, but okay we’re going to go off of what we did last week.

Dr. Stewart: Okay.

Kara Stewart-Mullens: Because last week was very interesting and I just don’t think people realize the importance of mitochondria.

Dr. Stewart: No.

Kara Stewart-Mullens: So we got through what mitochondria do and how key and necessary they are to function well. You went over the five steps which we’re going to cover again, but, you know, we talked about genetic weaknesses, but also we ended the show on something interesting. We talked about the poisoning of the mitochondria and where a lot of these things can get poisoned, so to speak. So before you start speaking…

Dr. Stewart: Yeah.

Kara Stewart-Mullens: I just want to preface that we’re going to cover the genetic weaknesses of the mitochondria and the poisoning of it. We’re also going to talk about some new findings that you talk about recently.

Dr. Stewart: Sure. Absolutely.

Kara Stewart-Mullens: Okay. Alright. Go (laughing).

Dr. Stewart: (laughing) Well, you know, poisoning is a…

Kara Stewart-Mullens: Hard term, right?

Dr. Stewart: It’s a pretty hard term. Obviously the status of the mitochondria before, depending on the person. What’s really unique about what’s gone on with genetic testing now is we can actually see the inside of the mitochondria from an enzymatic standpoint.

Kara Stewart-Mullens: And those are the five steps you’re talking about?

Dr. Stewart: Those are basically the five steps of the respiratory chain, okay?

Kara Stewart-Mullens: Okay.

Dr. Stewart: And, you know, those steps basically are the five steps that produce 90 percent of the energy in a cell…

Kara Stewart-Mullens: ACP?

Dr. Stewart: Mmm-hmm. Okay? Now the thing is, what we’re realizing is that there can be weaknesses in four out of those five steps and it actually defines the strength of the mitochondria. So basically an NFL football player will have mitochondria that will work about 90 percent. Okay?

Kara Stewart-Mullens: Yeah. You said athletes, your pro, right?

Dr. Stewart: Yeah. Well and the reason those guys are that way is because they are freaks because they got great energy.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: But if you’re operating at 60 percent in relative terms and we don’t know exactly how strong each of these little SNPs are, but we know that they obviously weaken the system…

Kara Stewart-Mullens: Yeah.

Dr. Stewart: You’re going to get into chronic fatigue, you’re not going to function well. You’re going to get into obviously more anxiety…

Kara Stewart-Mullens: Neurotransmitter function…

Dr. Stewart: Neurotransmitter problems and immune problems. So I like to tell patients think about a 90-year-old lady. Okay? So this 90-year-old lady is getting weak batteries. First thing to go is her nervous system, her brain doesn’t work well, she doesn’t move very quickly, etc. Then all of a sudden, she starts to get sickly. That’s the immune system starting to go…

Kara Stewart-Mullens: Shutting down.

Dr. Stewart: Okay? Then all of a sudden, the muscles don’t work any more and guess what, she can’t take care of herself anymore.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: And then eventually you’re going to lose her pretty soon after that. Okay?

Kara Stewart-Mullens: Yeah. You mentioned that last week and I was like…

Dr. Stewart: I understand…

Kara Stewart-Mullens: I understand.

Dr. Stewart: Very simple stuff. The reason that’s important is because you got to understand that those three systems; brain first, immune system second, muscles third, take most of the energy of the body.

Kara Stewart-Mullens: Yeah. I was shocked that when you said the mitochondria in the brain takes the most energy.

Dr. Stewart: Sure. Well it has to work all the time.

Kara Stewart-Mullens: I mean I guess so. It kind of takes control of…

Dr. Stewart: It never gets a rest. You have to rest your muscles. Okay?

Kara Stewart-Mullens: That’s true, yeah.

Dr. Stewart: Now the thing is depending on the status you have initially, if you go in there and you weaken the mitochondria with a chemical or you weaken it with a toxin, for instance, you certainly have a bigger problem than somebody who’s already got weak mitochondria.

Kara Stewart-Mullens: Yeah. There was a lot of information. You were right. If I went to Google and looked at all this stuff, I mean interesting research.

Dr. Stewart: Sure.

Kara Stewart-Mullens: Can I ask you one quick question?

Dr. Stewart: Sure.

Kara Stewart-Mullens: I don’t think people understand why the mitochondria are important for us for functionality. Why do doctors not go; “Oh we think your mitochondria is weak,” at your medical exam or your general practice exam?

Dr. Stewart: They couldn’t see it.

Kara Stewart-Mullens: Because they’re so small or we just didn’t know enough?

Dr. Stewart: No, we just never assumed it. Now we would see somebody who let’s say had floppy muscles or a floppy baby or we’d see these autistic kids with low muscle tone and poor muscle tone and we’d say; “Yeah those people probably have mitochondria weakness.” We never thought about, you or I, these normal people, somebody having much better batteries than somebody else.

Kara Stewart-Mullens: But still having an issue?

Dr. Stewart: Still having an issue because the problem is you got to feed these mitochondria something, that’s methylation. You have to feed methyltetrahydrofolate through a receptor that’s coated by the SLC19A1 and we find out that people who do not function as well can’t carry methyl folate into the mitochondria very well. So not only having a methylation problem…

Kara Stewart-Mullens: Ah…

Dr. Stewart: Primarily, if you can’t carry it, it makes it even worse in the mitochondria.

Kara Stewart-Mullens: That’s why you said start with methylation first, then go with the mitochondria?

Dr. Stewart: You got to put gas in it.

Kara Stewart-Mullens: Okay. So with the mitochondria SNPs, the five that you look at, can you name some of those for some of our listeners?

Dr. Stewart: Sure.

Kara Stewart-Mullens: That have their genetic testing…

Dr. Stewart: So the first one is NDUFS7.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? The second one is step two, you really don’t have to worry about it. It’s never defective.

Kara Stewart-Mullens: Okay.

Dr. Stewart: From what we can see.

Kara Stewart-Mullens: That’s good.

Dr. Stewart: Step three is coded by the UQCRC2 and that’s ubiquinone.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Cytochrome reductase. Then there’s COX5A and COX6C which handles step four…

Kara Stewart-Mullens: Ah…

Dr. Stewart: And then there’s ATP, different ATPases that handle our ATP production, enzyme that handle and are coded by the ATP G3 and C1…something like that.

Kara Stewart-Mullens: Okay. You passed the quiz.

Dr. Stewart: Okay.

Kara Stewart-Mullens: So if you go to a physician or a doctor that looks at genetic testing, he should be looking at those, they’re important?

Dr. Stewart: He should, but he doesn’t necessarily know that. He sees a respiratory chain of…

Kara Stewart-Mullens: Well that’s what you’re here for.

Dr. Stewart: Well that’s right because the respiratory chain is hard. This is hard chemistry, but unfortunately that makes 90 percent of the energy of the cell.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay?

Kara Stewart-Mullens: Well back to the toxic agents that can hurt the mitochondria. We’ve got pharmaceutical products.

Dr. Stewart: Yeah.

Kara Stewart-Mullens: We’ve got anesthesia, surgery, environmental agents, and diet. So let’s…

Dr. Stewart: Right.

Kara Stewart-Mullens: Let’s start with pharmaceuticals.

Dr. Stewart: Okay, you know, this is a very touchy subject, but remember…

Kara Stewart-Mullens: It is.

Dr. Stewart: That the FDA, I think they should actually look, in my opinion, at the potential toxicity of the mitochondria whenever they’re approving a drug. Okay?

Kara Stewart-Mullens: Yeah it says that it is not an FDA requirement…

Dr. Stewart: No.

Kara Stewart-Mullens: For drug approval, establishing mitochondrial toxicity.

Dr. Stewart: No. That is not true and that is true and that is a travesty to me.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: Okay?

Kara Stewart-Mullens: They’re taking something you think that’s going to help…

Dr. Stewart: So without a doubt, the pharmaceutical agent, the most severe is probably one form of the antibiotics called the quinolones. Okay?

Kara Stewart-Mullens: Yeah.

Dr. Stewart: The quinolones are Cipro, Avelox and they basically work by actually poisoning the mitochondria of bacteria.

Kara Stewart-Mullens: Okay. Because you’re so sick?

Dr. Stewart: Right.

Kara Stewart-Mullens: You have that bacteria so bad?

Dr. Stewart: Right. So the bacteria, you poison it and that’s how you kill it. The problem is if you got a weak mitochondria, those quinolones can poison your mitochondria.

Kara Stewart-Mullens: Oh gosh.

Dr. Stewart: Do you understand?

Kara Stewart-Mullens: And then you’re going to tell us how to get out of that.

Dr. Stewart: Well okay. Now the second thing they’ll tell you in certain antibiotics now is to take CoQ10. We’re finding out that doesn’t necessarily…

Kara Stewart-Mullens: It’s not in the right form?

Dr. Stewart: Well, that’s exactly right. Now the second group, believe it or not is the statins.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? And that’s going to be very controversial…

Kara Stewart-Mullens: A lot of people…

Dr. Stewart: But guess where cholesterol is interrupted, its metabolism is interrupted in a mitochondrial chain.

Kara Stewart-Mullens: Yeah. I read that when I was looking through your research.

Dr. Stewart: Okay. So the whole problem is you have these side effects that are very well known like myopathies, neuropathies, some people talk about encephalopathies and basically if you’ve got a weak mitochondria and then you throw in a statin, and you weaken the mitochondria more, you all of a sudden can make people’s brains, nervous systems and their muscles not work well.

Kara Stewart-Mullens: Wow.

Dr. Stewart: Do you understand?

Kara Stewart-Mullens: Yeah.

Dr. Stewart: And so they’ll always tell you to take CoQ10 with it. Well that doesn’t necessarily always work.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? Because it depends on your genetic alteration. Probably the third biggest category…

Kara Stewart-Mullens: Well, I found anticonvulsants…

Dr. Stewart: Well…

Kara Stewart-Mullens: Psychotropic drugs…

Dr. Stewart: Yeah. Psychotropic drugs are probably the third.

Kara Stewart-Mullens: So your Prozac…

Dr. Stewart: Which makes no sense because obviously neurological issues typically are, now that we can see it…

Kara Stewart-Mullens: Mitochondrial?

Dr. Stewart: Mitochondrial weakness and then you throw in this agent and all of a sudden, you may be making people worse.

Kara Stewart-Mullens: Is it because you’re depleting the neurotransmitter function? Do you think that’s what is causing the weakness of the mitochondria?

Dr. Stewart: No the weakness in the mitochondria is encoded.

Kara Stewart-Mullens: What does that mean?

Dr. Stewart: It means you’re born with it.

Kara Stewart-Mullens: Well I know, but what is the drug doing?

Dr. Stewart: The drug is basically interrupting the process.

Kara Stewart-Mullens: Oh okay. So those five steps are somehow interrupted?

Dr. Stewart: So the biggest problem is that you’ve got to look at some other things like how good you are at clearing chemicals because chemicals, byproducts of drugs, not the drug itself, but the breakdown of the drug and the byproduct, if you have inability to clear that…

Kara Stewart-Mullens: Okay.

Dr. Stewart: From a glutathione or from an intracellular antioxidant standpoint, you really can get more poison than you wish.

Kara Stewart-Mullens: Okay. At least if you’re methylating, with a lot of these drugs that you’re having to take or you think you need or the doctor thinks you need, at least you are kind of ahead of the game or helping yourself?

Dr. Stewart: A little bit ahead, we’re learning that obviously there is some faulty forms of glutathione present in many people.

Kara Stewart-Mullens: Goodness.

Dr. Stewart: Okay? There are some abnormal liver enzymes in the acetyltransferase system, there’s some abnormal SODs which clear oxidized sensors…

Kara Stewart-Mullens: Those are other SNPs?

Dr. Stewart: Those are other SNPs and basically we’re starting to put together this whole puzzle that is starting to make more sense as to why some people get sick and other people don’t.

Kara Stewart-Mullens:: Okay. So when some people get on these psychotropics or anticonvulsants, that was another big one, anesthesia, surgery, I mean that’s just kind of because you’re having a rough time in the body…

Dr. Stewart: Yes. So anesthesia, we’ll go with that because everybody worries about that.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: So in autism, where we have low muscle tone and obviously weak mitochondria in many kids, those parents all know to avoid anesthesia…

Kara Stewart-Mullens: Laughing gas, anything like that.

Dr. Stewart: Right. So it’s really the one we call the volatile camp compounds, the ones that are in gases that we breathe in to initiate anesthesia…

Kara Stewart-Mullens: Okay.

Dr. Stewart: And so obviously you can help protect yourself if you need to use those by putting something in to pull it back out. So we’ll use glutathione suppositories, high glutathiones…

Kara Stewart-Mullens: High doses…

Dr. Stewart: Glutathione lotions, we’ll do all kinds of things to try to get that back out because you need to be asleep when you’re doing surgery.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: Yeah. So the whole idea is we can tell the anesthesiologist, a lot of them don’t quite understand, its just the way they are. It’s interesting that…

Kara Stewart-Mullens: There’s some out there. I’ve come across one recently…

Dr. Stewart: Well it’s interesting…

Kara Stewart-Mullens: That’s really getting all this…

Dr. Stewart:I’ll tell you of my patients who are professional doctors or professionals and are physicians, anesthesiologists get it probably better than just about anybody.

Kara Stewart-Mullens: Oh really?

Dr. Stewart: Mmm-hmm.

Kara Stewart-Mullens: Why? Because they just understand that the body’s going to go through some serious breakdown?

Dr. Stewart: They’re really good chemists, but they also know that basically what they do is they take the body to the edge of death every day and bring it back…

Kara Stewart-Mullens: Oh. Interesting.

Dr. Stewart: So, you know, they really get this stuff. Obviously they tend to get sick if they’re exposed to those chemicals too…

Kara Stewart-Mullens: That’s the environmental factors?

Dr. Stewart: Mmm-hmm. So they’re really a clever group of doctors in my mind, especially as patients.

Kara Stewart-Mullens: So if you’re an anesthesiologist or you’re just a surgeon in general, I mean that’s one thing that I’ve found interesting with you, even 15 years ago, you’re always trying to give nutrition prior and post-surgery.

Dr. Stewart: Yeah. You got to prepare the patient for surgery.

Kara Stewart-Mullens: Because they’ve got to be able to extract those toxins.

Dr. Stewart: I used to tell my patients, we don’t just take an 80-year-old lady straight into surgery, you know…

Kara Stewart-Mullens: No.

Dr. Stewart: We try to get her beefed up a little bit, okay? We should actually beef up everybody before surgery…

Kara Stewart-Mullens: What do you mean, like gain weight or beef up nutritionally?

Dr. Stewart: Oh, gain weight nutritionally, all that because we knew that they wouldn’t…

Kara Stewart-Mullens: Well they tell you to stop smoking, stop drinking alcohol…

Dr. Stewart: Oh sure.

Kara Stewart-Mullens: For a reason, but there’s other ways…

Dr. Stewart: That’s another one, good thing you mentioned smoking. Tobacco smoke is a very notorious mitochondrial…

Kara Stewart-Mullens: Yeah.

Dr. Stewart: Devastation agents. So those chemicals and certain herbicides and pesticides are really well-known to hurt your mitochondria.

Kara Stewart-Mullens: Okay. Well we’re going to cut right there because when we get back, we’re going to talk about how to get that out of your system…

Dr. Stewart: Sure.

Kara Stewart-Mullens: You can get the mitochondria on the right track. Alright we’ll be right back with Coffee With Dr. Stewart.

Commercial Break:

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End Commercial Break

Kara Stewart-Mullens:

Alright everybody and we are back with episode 10, part two of Coffee With Dr. Stewart. We are talking about mitochondria fatigue, mitochondria, things that can hurt the mitochondria and, like I said in the beginning, I don’t think people understand how detrimental the mitochondria can be affected with a lot of things that we do. Right, Dr. Stewart?

Dr. Stewart: That’s right.

Kara Stewart-Mullens: We talked about pharmaceuticals, anesthesia, and environmental agents. So we ended the note on environmental agents, talking about smoking, talked about alcohol, talked about other chemicals that could get, like poisons, are you talking about like fertilizers and things like that?

Dr. Stewart: Absolutely. Insecticides.

Kara Stewart-Mullens: So I know that you deal with a lot of patients who’ve had some kind of environmental poisoning. What is your course of protocol when you know something’s going on?

Dr. Stewart: Well first of all, you got to let the patient know that they’re right.

Kara Stewart-Mullens: That they don’t feel good.

Dr. Stewart: Because most doctors will roll their eyes when people say that.

Kara Stewart-Mullens: It’s in your head?

Dr. Stewart: It’s in your head, you know, it’s just what they think is wrong with them, but it’s really not…

Kara Stewart-Mullens: I think that’s why so many people love you.

Dr. Stewart: Well the whole idea is my job is not to say whether you’re right or wrong, it’s to try to prove you right.

Kara Stewart-Mullens: Mmm-hmm.

Dr. Stewart: Okay? So if I can prove you right and get a good understanding of it, then you are right.

Kara Stewart-Mullens: But you hate to be wrong. I mean right.

Dr. Stewart: No, I don’t like to be wrong, but I certainly can own up to it if I am.

Kara Stewart-Mullens: Yeah. No, no, no, no. I was saying it in a sarcastic way.

Dr. Stewart: I understand. Well the whole idea is what was really unusual is how common this stuff really is and so basically, after reading about 12- to 1500 genetic reports, which is what I’ve read this year…

Kara Stewart-Mullens: Okay. Gosh…

Dr. Stewart: That there are basically three major areas that almost all my skewed sick patients wind up with. About 80 percent of them have a faulty glutathione, NAT system, which is basically…

Kara Stewart-Mullens: NAT is the SNP?

Dr. Stewart: Can’t remove chemicals very well because their glutathione is faulty or their chemical detoxifiers are faulty.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? So obviously that’s a big problem…

Kara Stewart-Mullens: And glutathione, just for everybody’s clarity, is what get toxins out of the body.

Dr. Stewart: Correct.

Kara Stewart-Mullens: It’s naturally there, supposed to be…

Dr. Stewart: What I’ve found is this highly sulfur contained, as what we call di-sulfhydryl groups that’s able to bind chemical toxins and take them from fat solubility and make them water soluble again so we can pee them out.

Kara Stewart-Mullens: Or sweat them out…

Dr. Stewart: Sweat them out, poop them out, etc.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Now the NAT system is the liver enzyme system that clears certain toxins and chemicals and there’s a cytochrome system which clears drug and that’s, all about how do we get these toxins…

Kara Stewart-Mullens: Out…

Dr. Stewart: To change their ability to stay in the body and that way we can excrete them.

Kara Stewart-Mullens: Okay.

Dr. Stewart: So when those are faulty, we’re really in trouble. Now glutathione is also a very powerful anti-inflammatory. In fact, I tell people it’s the second most powerful anti-inflammatory behind steroids.

Kara Stewart-Mullens: Is that why the cream is so popular for a lot of people that have masses or….

Dr. Stewart: Sure.

Kara Stewart-Mullens: Put it on areas that are inflamed.

Dr. Stewart: Well so God concentrates glutathione in your lungs, in your skin, in your bowel, in your sinuses, in your bladder, and around your nervous system.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Because we don’t want inflammation in those areas and those are also…

Kara Stewart-Mullens: Protection…

Dr. Stewart: Those are also where we get into toxins. So if you have interstitial cystitis or chronic GI irritation or asthma or eczema or other things, you probably have a faulty glutathione from what we can see. Now we’ve never thought about it that way. They thought you just had a jacked up immune system.

Kara Stewart-Mullens: Okay.

Dr. Stewart: But if you have a faulty glutathione, you can’t control inflammation in those areas.

Kara Stewart-Mullens: Well then therefore, your immune system suffers?

Dr. Stewart: Correct.

Kara Stewart-Mullens: Okay.

Dr. Stewart:Now because if we can’t clear out those chemicals, then essentially they’ve dolled up and eventually those byproducts and those chemical toxins that we…God wouldn’t have given us a chemical toxin cleanser if we didn’t need it…

Kara Stewart-Mullens: Exactly.

Dr. Stewart: Okay? So the whole idea is we get it from foods, we get it from the environment and if we can’t get rid of it well, eventually it will build up and cause us problems.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Now some people that may happen in five years, some people it may take 50 years.

Kara Stewart-Mullens: To stack up?

Dr. Stewart: To stack up.

Kara Stewart-Mullens: Okay. Then what can we do in the meantime? I mean I know we have lots of nutraceuticals for glutathione?

Dr. Stewart: So you can try to make more glutathione, but the key is and that’s what we used to do, but what we have realized now is if you have a faulty form, you’re just making a crappy form.

Kara Stewart-Mullens: But is it better to have a crappier form than none at all?

Dr. Stewart: I’d rather have the good stuff myself. Okay?

Kara Stewart-Mullens: Okay. So we can put it in neutraceutally?

Dr. Stewart: So we can put glutathione back in…

Kara Stewart-Mullens: I know you do IV glutathione at your clinic.

Dr. Stewart:Well, I’ve got sick people and these people…if I have weak mitochondria, I need to clean the filters, just like everybody cleans their air conditioner filters.

Kara Stewart-Mullens: I’ve gotten it a couple of times. I felt amazing.

Dr. Stewart: Yeah. What it does is it basically…you felt it from the anti-inflammatories…

Kara Stewart-Mullens: Oh yeah.

Dr. Stewart: Some people detox really hard.

Kara Stewart-Mullens: Well, I take that back because the first time I did detox really hard. I felt like a truck hit me and you said that’s the chemicals coming out. Then the next two times, I was good, it was great to have my energy levels back.

Dr. Stewart: Right. So that’s a high dose because glutathione smells to high heaven of sulphur.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: So trying to make it palatable in an oral…

Kara Stewart-Mullens: In a high dose…

Dr. Stewart: In a liposomal and a transdermal, it’s just really hard to do.

Kara Stewart-Mullens: Transdermal we’ve actually worked really hard on masking it. Now I haven’t found a liquid out there that tastes very good…

Dr. Stewart: No.

Kara Stewart-Mullens: At all…

Dr. Stewart: So we use suppositories which gives us a lot more and then we go to IVs when we really need it.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: The problem is expense; you know?

Kara Stewart-Mullens: Yeah.

Dr. Stewart: And expertise…

Kara Stewart-Mullens: And you got to take the time to sit there and let it drip.

Dr. Stewart: And you got to have expertise. I mean really giving glutathione IV is really not the easiest thing in the world.

Kara Stewart-Mullens: Okay.

Dr. Stewart: You can run into some problems but what we want to do is we want to get that cleaned out because we don’t need those chemicals in there messing up the mitochondria that may be already weak.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? So glutathione is going to be your friend. Okay?

Kara Stewart-Mullens: Alright.

Dr. Stewart: Now we can have some other bindings from alpha-lipoic acid and a few other things that can help us a little bit. Some people who have acetyl transferase problems, they can use a little bit of milk thistle, things like that to help, Synolyne and so, you know, those are in some of the products that we have like Toxiclear.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: Okay? So the long and the short of it is that once we want to get all that stuff out because it just doesn’t belong in us.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? Now the second thing we want to do is we want to take a person who has weak batteries and we want to try to strengthen them.

Kara Stewart-Mullens: Like putting the right stuff in?

Dr. Stewart: Yeah. So putting the right stuff in didn’t quite work.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? That was our Mitochondrial Restore and it’s great.

Kara Stewart-Mullens: I mean it does work.

Dr. Stewart: It does.

Kara Stewart-Mullens: We have a lot of people that think…

Dr. Stewart: It does, it works…

Kara Stewart-Mullens: It has done miracles…

Dr. Stewart: But it didn’t work at changing the status.

Kara Stewart-Mullens: Oh I see.

Dr. Stewart: Okay?

Kara Stewart-Mullens: It was kind of a temporary fix?

Dr. Stewart: So what’s really come around in the research in the last year or two is that we can add step one which is an NDUFS7, 8, and 3, is a very, very common weakness.

Kara Stewart-Mullens: Those are SNPs?

Dr. Stewart: Mmm-hmm.

Kara Stewart-Mullens: Okay. In your genes.

Dr. Stewart: Okay? And that’s the first step in the respiratory chain. Now that works on NADH.

Kara Stewart-Mullens: We talked about that last episode.

Dr. Stewart: Okay? We can use Niagen which is nicotinamide riboside, we can use NADH, and that tends to strengthen that step, but you got to be really careful because that works really quick and if you take a person who’s used to a low energy state in the brain and you change the energy status, a lot of people get freaked out.

Kara Stewart-Mullens: Yeah you said it made you very irritable.

Dr. Stewart: And I’ve heard that a lot.

Kara Stewart-Mullens: So you start with a half dose. Now we’re talking about the new formula that’s coming out in a few weeks…

Dr. Stewart: Right.

Kara Stewart-Mullens: It’s Mito Cell PQQ…

Dr. Stewart: Well and I’m getting to that really quick.

Kara Stewart-Mullens: Okay.

Dr. Stewart: So then the second thing which has really been the exciting thing and I actually had four people come to my office yesterday and said that PQQ has changed their life.

Kara Stewart-Mullens: I’ve already heard that many, many times, but I live it every day.

Dr. Stewart: Now what happens is PQQ is proven through some very scientific processes to actually induce the growth of more mitochondria in the cell.

Kara Stewart-Mullens: Okay.

Dr. Stewart: And what that does is if I got a battery…let’s say I have four batteries working at 60 percent. If I can make that six batteries working the 60 percent, I’ve got a whole lot more energy.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: Okay? So PQQ can make a significant change and so basically once we saw that all those things were happening, we decided to do our typical thing which was build a supplement that can take all those together.

Kara Stewart-Mullens: You do your typical thing. You build the formula.

Dr. Stewart: Right. We have decided to put PQQ and ubiquinone. Now ubiquinol could have been chosen, but ubiquinone is much more stable long term.

Kara Stewart-Mullens: Yep.

Dr. Stewart: And then we basically put some NADH in it and then we went ahead and put resveratrol and quercetin and some…

Kara Stewart-Mullens: A lot of anti-aging…

Dr. Stewart: Yeah. Basically to help the mitochondria work better.

Kara Stewart-Mullens: Okay.

Dr. Stewart: So and that’s what…

Kara Stewart-Mullens: You’ve got vitamin C, zinc…

Dr. Stewart: Mmm-hmm. So that’s what’s in the Mito Cell. Now you don’t have to take the Mito Cell. You can take any of these and Mito Cell might not be perfect for everybody because some people can handle immediate energy and some people can’t.

Kara Stewart-Mullens: Okay.

Dr. Stewart: But obviously what we’re trying to do is make it simplistic so you don’t have a whole lot of bottles…

Kara Stewart-Mullens: Well as I like to call it, the compression model.

Dr. Stewart: Correct.

Kara Stewart-Mullens: Why open six bottles when you can try and open one or two?

Dr. Stewart: That’s right. I can tell you that the stuff does work.

Kara Stewart-Mullens: Oh no we have the test back. We have the people that used it.

Dr. Stewart: If you can’t tell, I love talking about mitochondria because I finally can do something about it.

Kara Stewart-Mullens: I looked over your lecture that you’re speaking in December at the Anti-Aging World Congress and it was very over my head, so I have to admit that…

Dr. Stewart: Well I geeked out…

Kara Stewart-Mullens: I know and that’s good. You got one hour to impress like 700 doctors and see if they can get it and I just found it interesting just because from a research standpoint, you mention a lot of research articles and things. So this isn’t just pulling it out of the air.

Dr. Stewart: No. It’s just so new and general. All these articles that you read on mitochondrial poisons, is how you referred to it, we’re going to find out that the people that really get affected are the people who have mitochondrial genetic weakness.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: And so…

Kara Stewart-Mullens: That was my next question. If you do not have your genetic testing which a lot of people still don’t, how do you know you need the product? How do you know you need the Mito Cell?

Dr. Stewart: Okay. Well the typical things are exercise and tolerance…

Kara Stewart-Mullens: Like what you’re sore after exercising?

Dr. Stewart: No. You just have trouble rebounding.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Okay? Not just sore, everybody gets sore after a workout.

Kara Stewart-Mullens: Yeah.

Dr. Stewart: But really it takes a long time for you to get back to feeling normal.

Kara Stewart-Mullens: Oh.

Dr. Stewart: Like several days.

Kara Stewart-Mullens: Okay.

Dr. Stewart: Muscular weakness, fatigue, immune system that’s not quite working as well as it should, have trouble healing from injuries, just basically a low energy state but we’re probably going to be able to throw in anxiety and depression and post-traumatic stress disorder into those…

Kara Stewart-Mullens: Because they correlate.

Dr. Stewart: Mmm-hmm. Because…

Kara Stewart-Mullens: I saw that on a lot of literature I was reading last night.

Dr. Stewart: Because when your brain does not have enough energy, it can’t keep up. So really even…

Kara Stewart-Mullens: You go into a panic state?

Dr. Stewart: Even the ADD/ADHD realm. What I didn’t realize in the ADD realm is that the batteries were weak in a lot of those kids.

Kara Stewart-Mullens: Oh.

Dr. Stewart: So the brain would fart out in the afternoon…

Kara Stewart-Mullens: Great term.

Dr. Stewart: Do you understand?

Kara Stewart-Mullens: Yeah. Tired out...

Dr. Stewart: Because you’d ask the parents, well does your son do better in the morning and then have trouble in the afternoon? They’re like; “exactly”.

Kara Stewart-Mullens: Oh yeah.

Dr. Stewart: Even when he gets home, he’s fried. He can’t do any homework. Well guess what…

Kara Stewart-Mullens: That’s a lot of people.

Dr. Stewart: Well guess what?

Kara Stewart-Mullens: Yeah?

Dr. Stewart: The batteries were weak.

Kara Stewart-Mullens: Oh goodness. So if you don’t have your genetic testing, you can look at those symptoms and go okay, they might have a genetic SNP that’s affecting that…

Dr. Stewart: Correct.

Kara Stewart-Mullens: That five-step chain? Correct?

Dr. Stewart: Correct.

Kara Stewart-Mullens: You need to look at the SNPs. You name them. I don’t know.

Dr. Stewart: Okay. The SLC19A1, NDUFS7, 8 and 3.

Kara Stewart-Mullens: Okay.

Dr. Stewart: UQCRC2, COX5A, and COX6C…

Kara Stewart-Mullens: Now are we looking at homozygous which is two copies or a one copy state at heterozygous?

Dr. Stewart: One or two can be a problem.

Kara Stewart-Mullens: Really?

Dr. Stewart: Two is obviously worse.

Kara Stewart-Mullens: Same just with methylation?

Dr. Stewart: What I do is I count the positive and just add a simplicity, I give you a 10 percent weakness for every positive.

Kara Stewart-Mullens: Oh wow.

Dr. Stewart: Well within those…

Kara Stewart-Mullens: Yeah.

Dr. Stewart: Those groups.

Kara Stewart-Mullens: Those SNPs. Yeah.

Dr. Stewart: So if you have all the COX NDUFS7s or a COX6C and a 5A only give you a 10 percent.

Kara Stewart-Mullens: Okay. So then you definitely need to do something about it?

Dr. Stewart: And that’s not perfect science. That’s just giving me a general clinical feel.

Kara Stewart-Mullens: Well you have proof now because all your patients…

Dr. Stewart: Right.

Kara Stewart-Mullens: You confirmed that okay, this was what was going on.

Dr. Stewart: Correct.

Kara Stewart-Mullens: Alright. Man, good stuff. Very good stuff.

Dr. Stewart: Okay.

Kara Stewart-Mullens: And I’m excited that we got to talk about this and I think it’s going to open a lot of people’s eyes and maybe realize why they’re so tired all the time or just having issues in general. So we thank you for joining us on this episode. We hope you have a beautiful and blessed day and we’ll talk to you next week. Buh-bye.


This show is intended for general information and entertainment purposes only. Dr. Stewart serves as the chief science officer and lead formulator for Neurobiologix and advises you to consult with your own medical professional on any information given during this programming. This information is not intended to diagnose, treat, or cure any disease or medical condition.