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You are here: Home > FOLATE / Folinic Acid

Is your health suffering from a folic acid deficiency?
Folic acid occurs naturally as a complex of related substances called folates, found in sprouts, Brewers' yeast, liver and kidney.

However, levels are soon diminished following cooking and processing. And since most of us do not consume enough folate-rich foods, experts believe that many of us are suffering from a folic acid deficiency.

Furthermore, studies in healthy human participants show that folic acid is poorly absorbed from the diet anyway, which results in very little of the metabolically active form, methylfolate, being produced.

Folic acid undergoes a series of complicated vitamin and energy-dependent changes in your body, between your intestine and liver, before it is converted to its active form, methylfolate.

A break in any one of these processes resulting from dietary deficiency, malabsorption, can soon lead to low levels of methylfolate in your brain.

Now, new research suggests that neurological symptoms such as memory loss, sleep issues, irritability, forgetfulness, and mood issues may result.

Folinic acid, leucovorin, is a far more potent form of folic acid and 5-Methytetrahydrofolate is often used in conjuction for those that may need both for absorption into the blood brain barrier, nervous and immune systems.

Neurobiologix specializes in several products that contain forms of Folate, Folinic Acid and 5-Methyltetrahydrofolate. Most often, those that are poor methylators will need additional folate in some form.
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Bioactive B12 - Folate (60 Tablets/Chewables) Methyl Folate Plus - 90 Capsules
Our Price: $25.90
Our Price: $37.90
Methyl Folate Plus
High-potency, fast-dissolving tablets.

Bioactive B12 Folate® combines the active coenzyme form of vitamin B12, methylcobalamin, with an active form of folate, Metafolin®* L-5-methyltetrahydrofolate. This high-potency, bioactive formula was created to bypass normal absorptive mechanisms for vitamin B12 and folate which may be impaired due to aging, illness, or gastrointestinal surgery.

Fast-dissolving tablets allow for quick release into the bloodstream. Vitamin B12 and folate play an integral role in DNA synthesis and thus are essential to cell division and proper functioning of virtually all tissues in the body.

Vitamin B12 and folate also participate in methylation and proper metabolism of homocysteine, a potentially toxic metabolite of methionine. Dietary B12 can be reliably obtained only from animal products and is a singularly difficult vitamin to absorb. Active B12-Folate may be especially beneficial for vegetarians and persons with impaired gastrointestinal absorptive function due to aging, illness, surgery or a methylation deficiency.
Improved Formula Now With 30mg Vitamin B2 (Riboflavin-5-Phosphate)

This formula is an Optimal methylation formula with activating co-factor created by Kendal Stewart, MD to support the methylation pathway and provide adequate Folinic Acid (leucovorin) for those suffering from moderate to severe neuro-immune syndromes.


Methyl Folate Plus™ is designed to be used in conjunction with the Neuro-Immune Stabilizer Topical Cream that provides the activating co-factors to deliver the additional tetrahydrofolate to support neurological and immune recovery. Most often poor methylators will need additional folinic acid.

Niacinamide helps support the mitochondria and supports as a cofactor for the other ingredients.


The typical indications for this product include but are not limited to:

* Presence of Folate Receptor Autoantibodies

*Homozygous (2 copies) MTHFR polymorphism

*Increased requirement for development (age 8-20)

*Acute recovery from major neurological injuries

*Moderate to severe autism spectrum issues

*Recovery from traumatic injury or surgery

(i.e. Head injury, stroke, neuritis, etc...)


Dr. Stewart Discusses Methyl Folate Plus and It's Use for Neuro-Immune Syndromes from Neurobiologix on Vimeo.

Bio Source Essentials Liquid (Berry/Citrus Flavor) / 32 Servings Methylation Complete Sublingual (120 Tabs) Natural Fruit Punch Flavor
Our Price: $38.90
Deal of the Day Price: $33.90
Our Price: $53.90
neuro methylation cream
New & Improved Taste! Berry Citrus That Everyone Will Love!

Powerful Liquid For The Body & Brain That Contains:
  • Multi-Vitamins
  • Cell Ready Minerals
  • Omega 3 Fatty Acids
  • Phyto-Nutrients
  • Anti-Oxidants
  • Enzymes

Benefits of Liquid Vitamins:

Enjoy Benefits of Immediate Absorption
Liquid vitamins and minerals are available for immediate absorption... do not have to be dissolved first like pills and tablets.

Ultimate Methylation Support
Sublingual tablet for Neurological, Nervous & Immune System Support

Our unique sublingual delivery system assures that our pharmaceutical grade Methylation Complete™ promotes and enhances the methylation processes needed to improve the production of glutathione, and allow maximum B12, B6 and 5-MTHF (bioactive form of folic acid) delivery to the nervous and immune systems. This sublingual may help maximize and aid in:
  • Mood Improvement & Stabilization
  • Mental Focus & Concentration
  • Organization Skills
  • MTHR Mutations
  • Short Term Memory
  • Cerebral Folate Deficiency
  • Hormonal Regulation
  • Sleep Patterns
  • Immune Function

Neuro-Immune Stabilizer Topical Cream (120 pumps)
Our Price: $54.90
neuro methylation cream

Now Available! Enhanced Formula With Additional 5-Methyltetrahydrofolate (5-MTHF) and Improved Delivery System!
Topical Cream for Neurological, Nervous & Immune System Support

As a solution, our unique topical delivery system, assures that our pharmaceutical grade Neuro-Immune Stabilizer Cream promotes and enhances the methylation processes needed to improve the production of glutathione, increase Vitamin D levels and allow maximum B12, B6 and vitamin delivery to the nervous and immune systems. This potent nutrient-rich cream may help maximize and aid in:
  • Mood Improvement & Stabilization
  • Mental Focus & Concentration
  • Organization Skills
  • 5 MTHR Mutation
  • Short Term Memory Loss
  • Cerebral Folate Deficiency
  • Hormonal Regulation
  • Sleep Patterns
  • Immune Function
Such nutrients as Pyridoxal 5-Phosphate (B6) and Vitamin B12 in a methylated form called methylcobalamin (Methyl B12) and hydroxycobalamin (Hydroxy B12) and natural Vitamin D assist the body neurologically and physically.

Roughly one in three Americans have genetically inefficient enzymes that help create 5-MTHF (folinic acid) so this cream will assist with supplying the 5-MTHF for optimal help.